Mixing comedy with a thorough investigation of psychedelics, the film explores the pros, cons, science, history, future, pop cultural impact, and cosmic possibilities of hallucinogens. The documentary features comedic tripping stories from A-list actors, comedians, and musicians. Star-studded reenactments and trippy animations bring their surreal hallucinations to life.
'Have a Good Trip' tackles the big questions: Can psychedelics have a powerful role in treating depression, addiction, and helping us confront our own mortality? Are we all made of the same stuff? Is love really all we need? Can trees talk?

The Spirit Molecule investigates dimethyltryptamine (DMT), a naturally occurring psychoactive compound, which exists in humans, and potentially every living organism. Utilizing Dr. Rick Strassman's government-sanctioned, human DMT research as the documentary's backbone, the study's potential impact and its inconceivable revelations emerge. A closer examination of DMT's effects through two traditionally opposed concepts, science and spirituality, The Spirit Molecule unravels the connections between cutting-edge neuroscience, quantum mechanics and human spirituality.
The Spirit Molecule, a simple molecule with enormous implications. The subtle combination of science, spirituality, and philosophy results in an abundance of incredible ideas and theories that could alter the way we understand the nature of reality and our relationship to it.

The final episode of this series looks at what happens to the brain when someone uses psychedelic drugs. It looks at how psychedelic drugs may be useful in dealing with anxiety in cancer survivors and serious depression. It explores the history of psychedelics and examines early medical experimentation with the drug. It also discussed why psychedelics were banned and examines how they affect the brain.